This edition of the Guide for the Care and Use of Laboratory Animals (the Guide) strongly affirms the principle that all who care for, use, or produce animals for research, testing, or teaching must assume responsibility for their well-being. The IACUC serves as a resource to faculty, staff, and students, providing guidance in fulfilling the obligation to plan and conduct all animal use procedures with the highest scientific, humane, and ethical principles, and has the authority to negotiate modifications and suspend or terminate animal activities deemed not in compliance with regulations and best practice. It is best practice to wear laboratory coats when working with animals in the laboratory as well. var new_q = "site:legal.uncc.edu/policies " + current_q; If you would like to continue using JoVE, please let your librarian know as they consider the most appropriate subscription options for your institution’s academic community. The IACUC, appointed by the Institutional Official, is recognized as the principal point of communication about laboratory animal and use issues for the University. If your institution received a request to send its USDA Inspection Report to ACURO, that is a legitimate request/email. Switch between the Original Pages, where you can read the report as it appeared in print, and Text Pages for the web version, where you can highlight and search the text. element.value = ''; Animal use is defined as the proper care, use, and humane treatment of laboratory animals produced for or used in research, testing, or teaching. Greenbelt MD: Scientists Center for Animal Welfare. NCB [Nuffield Council on Bioethics]. Available at http://ecfr.gpoaccess.gov/cgi/t/text/text-idx?sid=8314313bd7adf2c9f1964e2d82a88d92andc=ecfrandtpl=/ecfrbrowse/Title09/9cfrv1_02.tpl; accessed January 14, 2010. Do you want to take a quick tour of the OpenBook's features? Principles are broader in their scope and intended application, and are accepted generalizations about a topic that are frequently endorsed by many and diverse organizations (e.g., the U.S. Government Principles). Also, you can type in a page number and press Enter to go directly to that page in the book. “Acceptable method” - As defined by the American Veterinary Medical Association, an acceptable method of euthanasia renders an animal unconscious and insensitive to pain and distress as quickly as possible, followed by cessation of all respiratory and circulatory functions and brain activity. • Animals are susceptible to many of the same health problems as humans – cancer, diabetes, heart disease, etc. 1959. … Performance standard means a standard or guideline that, while describing a desired outcome, provides flexibility in achieving this outcome by granting discretion to those responsible for managing the animal care and use program, the researcher, and the IACUC. Students taking part in such procedures must be appropriately instructed and supervised. The number of animals used for a research project will be the minimum number necessary to produce scientifically valid results, and, where possible, animal research will be replaced by alternative methods. { Refinement and reduction goals should be balanced on a case-by-case basis. Accreditation bodies will find the Guide useful for evaluating many areas of animal care and use programs not subject to strict engineering standards (see definition below). Russell and R.L. However, those who use animals are morally and legally obligated to care for them properly and use them humanely. Burch published a practical strategy of replacement, refinement, and reduction—referred to as the Three Rs—for researchers to apply when considering experimental. Available at http://oacu.od.nih.gov/regs/USGovtPrncpl.htm; accessed May 10, 2010. Procedures involving animals must be performed by, or be closely supervised by a faculty or staff member who is skilled in the procedure. The screening follows guidelines and requirements from the Association for the Assessment and Accreditation of Laboratory Animal Care (AAALAC), International and the UW Institutional Animal Care … The University is committed to maintaining that accreditation, and each faculty member, staff member, or student involved in the use of animals is responsible for protecting their welfare and for knowing, understanding, and complying with applicable laws. Ideally, engineering and performance standards are balanced, setting a target for optimal practices, management, and operations while encouraging flexibility and judgment, if appropriate, based on individual situations (Gonder et al. Laboratory personnel must wear laboratory coats when working with animals in the vivarium. Any misuse of laboratory animals whether intentional or unwitting, will be addressed. Significant benefits to the health and welfare of both animals and humans have resulted from animal use in research, and continued use is crucial to future advancements. In addition, faculty investigators are responsible for completing periodic training to remain current on federal, state, and local regulations, University policies and procedures, and animal care and use technology. function clearContents(element) { For topics on which information is insufficient or incomplete, sustained research into improved methods of laboratory animal management, care, and use is needed for the continued evaluation and improvement of performance and engineering standards. A respected resource for decades, the Guide for the Care and Use of Laboratory Animals has been updated by a committee of experts, taking into consideration input from the scientific and laboratory animal communities and the public at large. 1992. The Institute for Laboratory Animal Research (ILAR), is a private, non-governmental, non-profit organization that promotes high-quality science through humane animal research and implementation of alternatives. The Guide incorporates new scientific information on common laboratory animals, including aquatic species, and includes extensive references. document.getElementById('google-search-policy-q').value = new_q; The goal of the Guide is to promote the humane care and use of laboratory animals by providing information that will enhance animal wellbeing, the quality of research, and the advancement of scientific knowledge that is relevant to both humans and animals. Public Health Service Policy on Humane Care and Use of Laboratory Animals. 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